Funded Projects

We are funded by: UK BBSRC, MRC, NERC, Wellcome Trust, as well as the European Commission (EC), USA National Institutes of Health (NIH), and pharmas.

Ongoing

2019-open: USA NIH “Common Fund Data Ecosystem - PIs: Owen White University of Maryland, USA; Avi Maayan, The Icahn School of Medicine at Mount Sinai, USA; Titus Brown, University of California, Davis, USA; Sansone SA, Oxford. A joint project to improve the FAIRness (Findable, Accessible, Interoperable, and Reusable) of four complex Common Fund dataset from the Gabriella Miller Kids First Pediatric Research (Kids First), Genotype Tissue Expression (GTEx), Library of Integrated Network-based Cellular Signatures (LINCS), and Human Microbiome Project (HMP) programs.

2019-2023: Wellcome Trust “FAIRsharing service: supporting the research life cycle - PI: Sansone SA. Development of a high-quality service to accelerate discovery, selection and use of repositories, standards, policies; increasing their producers’ satisfaction in terms of visibility, reuse and citations of the resources, and consumers guidance.

2019-2023: EC H2020 “EOSC-Life: infrastructure for life science data - Lead PI: Niklas Blomberg, ELIXIR Hub; Oxford PI: Sansone SA. A joint project between 39 institutions (leading major Europe’s biological and medical sciences’ research infrastructures) to achieve a shared vision of an open collaborative digital space for European Life Science and biomedical scientists. We lead on the creation of a tool to assess the level of data readiness (in terms of findability, accessibility, interoperability and reusability).

2019-2022: EC and EFPIA IMI “FAIRplus - making life science data FAIR - Lead PI: Niklas Blomberg, ELIXIR Hub; Oxford PI: Sansone SA. Joint project with ELIXIR Hub, several Nodes and pharmas (AstraZeneca, Janssen, Eli Lilly, GSK, Novartis, Bayer and Boehringer Ingelheim) to develop guidelines and tools to make data findable, accessible, interoperable and reusable, according to the FAIR principles. We lead on the design of the data FAIRness activities, including a FAIR Maturity Model and a FAIR Cookbook.

2018-2021: Wellcome Trust “ISA and InterMine: accelerating and rewarding data sharing” - PIs: Sansone SA, Oxford; Gos Micklem, University of Cambridge. A joint project to further develop and combine ISA and InterMine into an integrated system implementing a workflow to incentivise metadata collection, and the ability to automatically find, collect, integrate, reuse and publish data. We drive the ISA component and the collaboration with journal editors and publishers.

<2018-2020: ELIXIR Hub “Biocuration Landscape - Oxford PI: Sansone SA, McQuilton P. Funded by the ELIXIR Hub, this 1-year implementation study enable the engagement with other ELIXIR Nodes to map the landscape of biocuration in ELIXIR, looking at practice, capability and training requirements, as well to ensure that relevant resources are registered in FAIRsharing.

2018-2019: ELIXIR Hub “Data FAIRification - Oxford PI: Sansone SA. Funded by the ELIXIR Hub, this 1-year implementation study enable the engagement with other ELIXIR Nodes to define and improve the level of FAIRness of the ELIXIR Core Data resources.

2018-2019: ELIXIR Hub “Data Validation - Oxford PI: Sansone SA, Rocca-Serra P. Funded by the ELIXIR Hub, this 1-year implementation study enable the engagement with other ELIXIR Nodes to determine the requirements for data validation according to community-defined minimum information reporting checklists.

2017-2021: EC and ESFRI Innovative Medicines Initiative (IMI) “IMPRiND: inhibiting misfolded protein propagation in neurodegenerative diseases” Lead and Oxford PI: George Tofaris, Oxford co-I: Sansone SA. Part of Europe’s largest public-private initiative, this consortium of pharmas and academics works to identify druggable targets modulating misfolded proteins in Alzheimer’s and Parkinson’s diseases. We lead on the data curation and management activities.

2015-2019: EC H2020 “ELIXIR-EXCELERATE: fast-track ELIXIR implementation and drive early user exploitation across the life sciences” Lead PI: Niklas Blomberg, ELIXIR Hub; Oxford PI: Sansone SA. Coordinated by the ELIXIR Hub, the project involves 46 partners from 17 countries to help ELIXIR coordinate and extend national and international data resources and ensure the delivery of world-leading data services, supporting all sectors of life science R&D. We lead on several data interoperability and training related activities.

Completed (from 2010 only)

2017-2018: USA NIH BD2K Data Commons Pilot “Cloud agnostic architecture to safely access, reuse indexed FAIR objects” - Lead PI: Lucila Ohno-Machado, UCSD, USA; Oxford PI: Sansone SA.

2017-2018: USA NIH BD2K Data Commons Pilot “Facilitation center” - Lead PI: Owen White University of Maryland, USA; Oxford PI: Sansone SA.

2017-2018: USA NIH BD2K Data Commons Pilot “Development and implementation plan for community supported FAIR guidelines and metrics” - Lead PI: Avi Maayan, The Icahn School of Medicine at Mount Sinai, USA; Oxford PI: Sansone SA.

2017-2018: ELIXIR Hub “BioSchemas: extending schema.org for life science data” Lead PI: Rafael Jimenez, ELIXIR Hub; Oxford PI: Sansone SA.

2015-2018: EC H2020 “MultiMot: infrastructure for cell migration data” Lead PI: Lennart Martens, VIB, Belgium; Oxford PI: Sansone SA.

2015-2018: EC H2020 “PhenoMeNal: infrastructure for phenome and metabolome analysis” Lead PI: Christoph Steinbeck, EBI; Oxford PI: Sansone SA.

2015-2018: UK BBSRC “COPO: collaborative open plant omics infrastructure” Oxford PI: Sansone SA.

2015-2018: UK BBSRC “China-UK collaboration: sharing of metabolomics data and their analyses” - PI: Sansone SA- travel award.

2014-2018: USA NIH BD2K “CEDAR: centre for extended data annotation and retrieval” Lead PI: Mark Musen, Stanford, USA; Oxford PI: Sansone SA.

2014-2018: USA NIH BD2K “bioCADDIE: biomedical healthcare data discovery and indexing engine” Lead PI: Lucila Ohno-Machado, UCSD, USA; Oxford PI: Sansone SA.

2014-2017: UK MRC, BBSRC and NERC “Delivering the ELIXIR UK Node” Oxford PI: Sansone SA.

2012-2017: EC and EFPIA IMI “eTRIKS: European translational information and knowledge management services” Lead PI: Yike Guo, Imperial College, UK; Oxford PI: Sansone SA (joined in 2014).

2012-2015: EC FP7 “COSMOS: infrastructure, standards for metabolomics data” Lead PI: Christoph Steinbeck, EBI; Oxford PI: Sansone SA.

2012-2015: UK BBSRC “UK-China partnership: establishing common standards and curation practices” - PI: Sansone SA - travel award.

2011-2015: UK BBSRC and NERC “Building a global metagenomics portal to handle next-generation sequencing data and associated metadata” EBI PI: Sarah Hunter; Oxford PI: Sansone SA.

2010-2014: UK BBSRC and NERC “Omics data sharing: the Investigation / Study / Assay (ISA) Infrastructure” Lead PI: Sansone SA; NERC CEH PI: Dawn Field.