Funded Projects

We are funded by: UKRI (BBSRC, MRC, NERC), Wellcome Trust, as well as the European Commission (EC), USA National Institutes of Health (NIH), and pharmas.

New and ongoing

2021-2026: EU H2020 “Precision Toxicology” - Lead PI: John Colbourne, University of Birmingham, UK; University of Oxford PI: Sansone SA, Co-I: Rocca-Serra. A consortium of 16 organizations, including the USA NIH, to establish a new testing paradigm for chemical safety assessment, which identifies molecular key event biomarkers predictive of chemically induced adverse health effects in humans and facilitates their uptake into regulatory and industry practice.

2021-2023: UKRI “ELIXIR-UK: FAIR Data Stewardship Training” - PIs: Krzysztof Poterlowicz, University of Bradford; Robert Andrew, Cardiff University; Neil Hall, Earlham Institute; Carole Goble, University of Manchester; Sansone SA, University of Oxford. Joint project with key ELIXIR-UK institutes to establish a national data stewardship training programme, exploiting our ELIXIR-UK Node network of 18 member organisations, to deliver and embed training within UK universities and institutions.

2019-open: USA NIH “Common Fund Data Ecosystem - PIs: Owen White University of Maryland, USA; Avi Maayan, The Icahn School of Medicine at Mount Sinai, USA; Titus Brown, University of California, Davis, USA; Sansone SA, University of Oxford. A joint project to improve the FAIRness (Findable, Accessible, Interoperable, and Reusable) of four complex Common Fund dataset from the Gabriella Miller Kids First Pediatric Research (Kids First), Genotype Tissue Expression (GTEx), Library of Integrated Network-based Cellular Signatures (LINCS), and Human Microbiome Project (HMP) programs.

2019-2023: Wellcome Trust “FAIRsharing service: supporting the research life cycle - PI: Sansone, University of Oxford. Development of a high-quality service to accelerate discovery, selection and use of repositories, standards, policies; increasing their producers’ satisfaction in terms of visibility, reuse and citations of the resources, and consumers guidance.

2019-2023: EU H2020 “EOSC-Life: infrastructure for life science data - Lead PI: Niklas Blomberg, ELIXIR Hub; University of Oxford PI: Sansone. A joint project between 39 institutions (leading major Europe’s biological and medical sciences’ research infrastructures) to achieve a shared vision of an open collaborative digital space for European Life Science and biomedical scientists. We lead on the creation of a tool to assess the level of data readiness (in terms of findability, accessibility, interoperability and reusability).

2019-2022: EU and EFPIA IMI “FAIRplus - making life science data FAIR - Lead PI: Niklas Blomberg, ELIXIR Hub; University of Oxford PI: Sansone, Co-I: Rocca-Serra. Joint project with ELIXIR Hub, several Nodes and pharmas (AstraZeneca, Janssen, Eli Lilly, GSK, Novartis, Bayer and Boehringer Ingelheim) to develop guidelines and tools to make data findable, accessible, interoperable and reusable, according to the FAIR principles. We lead on the design of the data FAIRness activities, including a FAIR Maturity Model and a FAIR Cookbook.

2018-2022: Wellcome Trust “ISA and InterMine: accelerating and rewarding data sharing” - PIs: Sansone, University of Oxford; Gos Micklem, University of Cambridge. A joint project to further develop and combine ISA and InterMine into an integrated system implementing a workflow to incentivise metadata collection, and the ability to automatically find, collect, integrate, reuse and publish data. We drive the ISA component and the collaboration with journal editors and publishers.

2018-2021: ELIXIR Hub “Interoperability Platform: Implementation Studies” - University of Oxford PIs: Sansone, Rocca-Serra, McQuilton. Contribution to the activities of the “Interoperability Platform”, and a set of implementation studies (in collaboration with ELIXIR Nodes) on data interoperability aspects: “Bioschemas for Data Discoverability”, “Data FAIRification", "Biocuration Landscape”, "Data Validation", “Fluxomics Data Standardization”

2017-2021: EU and ESFRI Innovative Medicines Initiative (IMI) “IMPRiND: inhibiting misfolded protein propagation in neurodegenerative diseases” - Lead and University of Oxford PI: George Tofaris, Co-Is: Sansone, Rocca-Serra. Part of Europe’s largest public-private initiative, this consortium of pharmas and academics works to identify druggable targets modulating misfolded proteins in Alzheimer’s and Parkinson’s diseases. We lead on the data curation and management activities.

2017-2021: UK BBSRC “Japan-UK collaboration: sharing of metabolomics data and their analyses” - PIs: Sansone, University of Oxford. Strengthen relations with the National Bioscience Database Center to better link FAIRsharing and the Integbio catalogue, towards a fully synchronised content transfer workflow to better serve the research and publisher community.

Completed (when in Oxford)

2015-2019: EU H2020 “ELIXIR-EXCELERATE: fast-track ELIXIR implementation and drive early user exploitation across the life sciences” Lead PI: Niklas Blomberg, ELIXIR Hub; University of Oxford PI: Sansone. Coordinated by the ELIXIR Hub, the project involves 46 partners from 17 countries to help ELIXIR coordinate and extend national and international data resources and ensure the delivery of world-leading data services, supporting all sectors of life science R&D. We lead on several data interoperability and training related activities.

2017-2018: USA NIH BD2K Data Commons Pilot “Cloud agnostic architecture to safely access, reuse indexed FAIR objects” - Lead PI: Lucila Ohno-Machado, UCSD, USA; University of Oxford PI: Sansone.

2017-2018: USA NIH BD2K Data Commons Pilot “Facilitation center” - Lead PI: Owen White University of Maryland, USA; University of Oxford PI: Sansone.

2017-2018: USA NIH BD2K Data Commons Pilot “Development and implementation plan for community supported FAIR guidelines and metrics” - Lead PI: Avi Maayan, The Icahn School of Medicine at Mount Sinai, USA; University of Oxford PI: Sansone.

2015-2018: EU H2020 “MultiMot: infrastructure for cell migration data” Lead PI: Lennart Martens, VIB, Belgium; University of Oxford PI: Sansone, Co-I: Rocca-Serra.

2015-2018: EU H2020 “PhenoMeNal: infrastructure for phenome and metabolome analysis” Lead PI: Christoph Steinbeck, EBI; University of Oxford PI: Sansone, Co-I: Rocca-Serra.

2015-2018: UK BBSRC “COPO: collaborative open plant omics infrastructure” University of Oxford PI: Sansone, Co-I: Rocca-Serra.

2015-2018: UK BBSRC “China-UK collaboration: sharing of metabolomics data and their analyses” - PI: Sansone, University of Oxford - travel award.

2014-2018: USA NIH BD2K “CEDAR: centre for extended data annotation and retrieval” Lead PI: Mark Musen, Stanford, USA; University of Oxford PI: Sansone, Co-I: Rocca-Serra.

2014-2018: USA NIH BD2K “bioCADDIE: biomedical healthcare data discovery and indexing engine” Lead PI: Lucila Ohno-Machado, UCSD, USA; University of Oxford PI: Sansone, co-I: Rocca-Serra.

2014-2017: UK MRC, BBSRC and NERC “Delivering the ELIXIR UK Node” University of Oxford PI: Sansone.

2012-2017: EU and EFPIA IMI “eTRIKS: European translational information and knowledge management services” Lead PI: Yike Guo, Imperial College, UK; University of Oxford PI: Sansone, Co-I: Rocca-Serra (joined in 2014).

2012-2015: EU FP7 “COSMOS: infrastructure, standards for metabolomics data” Lead PI: Christoph Steinbeck, EBI; University of Oxford PI: Sansone.

2012-2015: UK BBSRC “UK-China partnership: establishing common standards and curation practices” - University of Oxford PI: Sansone - travel award.

2011-2015: UK BBSRC and NERC “Building a global metagenomics portal to handle next-generation sequencing data and associated metadata” EBI PI: Sarah Hunter; University of Oxford PI: Sansone, Co-I: Rocca-Serra.

2010-2014: UK BBSRC and NERC “Omics data sharing: the Investigation / Study / Assay (ISA) Infrastructure” Lead PI: Sansone, University of Oxford; NERC CEH PI: Dawn Field.

Completed (when at EMBL-EBI)

2009-2010: UK BBSRC, “MICheckout: Supporting Compliance with Consensus Reporting Requirements” - EMBL-EBI co-I: Sansone.

2007-2010: UK BBSRC, “Omics Data Standards: Synergy and Implementations” - EMBL-EBI PI: Sansone.

2007-2010: UK NERC Bioinformatics Centre, partnership funds - EMBL-EBI PI: Sansone.

2006-2010: EU FP6, “Carcinogenomics" - EMBL-EBI PI: Sansone.

2006-2008: UK BBSRC, “Ontology for Reporting Multi-Omics Experiments” - EMBL-EBI PI: Sansone.

2004-2008: EU FP6, “Nugo Nutrigenomics" - EMBL-EBI PI: Sansone.

2004-2007: NIH NIEHS, partnership funds - EMBL-EBI PI: Sansone.